Fans are wondering if the upcoming Hulu series, The Twisted Tale of Amanda Knoxis based on a true story. It is a crime drama with Grace van Patten in the lead role as Amanda Knox. With its August 20, 2025 release, the series has already caught the attention of crime drama fans.
Here’s what we know about the story so far.
Yes, Hulu’s The Twisted Tale of Amanda Knox is based on a real incident.
Amanda Knox was an exchange student in Perugia, Italy, in 2007. She was wrongfully accused of murdering her roommate, Meredith Kercher, after Kercher was found dead in their apartment.
Knox shared an apartment with Kercher while studying in Perugia. On November 1, 2007, Kercher was found dead in her room, having been sexually assaulted and stabbed to death (via The New York Times).
After discovering Kercher’s body, Amanda Knox and her then-boyfriend, Raffaele Sollecito, were arrested and interrogated without legal representation. During questioning, Knox falsely accused her employer, Patrick Lumumba, of involvement in the murder. Lumumba was jailed for two weeks before police proved his innocence and cleared him. This shifted attention back to Knox and Sollecito, who were then officially charged with Meredith Kercher’s murder.
Later, Rudy Guede, a known drug dealer, was arrested after his DNA was found at the crime scene. Despite Guede’s arrest, Knox and Sollecito remained on trial.
During the trial, Knox was sentenced to 28 and a half years in prison. When the case went to the appeal court in 2010, experts argued that evidence might have been contaminated. The alleged murder weapon did not contain Kercher’s or Knox’s DNA, and lapses in forensic procedures were highlighted. The court eventually found the couple not guilty, and they were released from prison in 2011.
Years later, Amanda Knox returned to Italy and spoke about how the media twisted her image and what it was like to endure the trial.
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